Original link: https://kaopubear.top/blog/2022-12-04-kaopubear-newsletter-intro/
After a period of preparation and adjustment (actually a long time), the Xiongyan Xiongyu member newsletter will resume next week and continue to be updated. The following is the latest email content to share with you~
written in front
Hello, I’m Thinking Bear, it’s a pleasure to meet you through this email (letter). Zhanxinjia~
If you’re surprised to receive this email, chances are we’ve connected for three reasons.
The first possibility : The Xiongyan Xiongyu member newsletter will be updated in December 2020, and the update will be suspended until July 2021. There is a high probability that you subscribed to this newsletter at that time, which is why the subject number of this issue’s email is “” 009″ instead of “001”.
The second possibility : Maybe you have studied the “Introduction to RNA-seq Transcriptome Data Analysis Practical Combat” course that was published at Station B and sought information. I don’t know if this course will help you in the end. Now it has surpassed 110,000 plays.
The third possibility : Maybe you are a listener of the podcast “Xiongyan Xiongyu”. I once heard me chat with three or five friends about study, work and harvest confusion, and helped me fill out the listener questionnaire. Cough, it was a year and a half ago that the podcast was updated normally. I hope I can return to you in another way without waiting too long.
If you read this email through other channels, you may wish to directly scan the QR code below or jump to the email newsletter subscription page , and continue reading after subscribing.
Why continue to update at this time
The Xiongyan Xiongyu member newsletter will start next week (December 5, 2022), and this Newsletter will continue to be updated.
The time to suspend the update in July 2021 is the node when I officially changed from a student status to a worker in the workplace. At that time, I felt that I had started a completely different life, and I needed to spend more energy to meet this change of identity. Now, after a year and a half, I can’t say that I have fully adapted to everything, but I have basically adapted to the status of a worker, so some things can continue .
From the suspension of updates to today, with no publicity and promotion at all, nearly 1,000 people have added subscriptions. Everyone found this way to keep in touch from the Xiongyan Xiongyu official account, from blogs and podcasts, but it seems that they have never been contacted again. Every time I see a new subscription to the subscription list, I feel anticipation and trust, so some things need to continue .
In the one and a half years since I started working, I was lucky enough to find an industry and team that I recognized, and even luckier to be doing something I was interested in. I have the opportunity to get in touch with clinical experiment projects and tumor-related data mining from the perspective of biological information, to the biomedical industry from the perspective of scientific research, and to see that my research results may be converted into decision-making references for clinical medicine.
Of course, work is different from when we were studying. What we are involved in is a part of a complex system. Whether and how to advance a project requires evaluation and consideration from many aspects. Many variables are beyond the control of individuals. The process of work is a process of trade-offs. It is necessary to weigh costs and benefits, as well as time and manpower. Among these trade-offs, maybe you and I should do some things that don’t require too many concerns, such as investing regardless of ROI and paying regardless of benefits, so some things should continue .
How this newsletter will be updated in the future
Xiongyan Xiongyu member newsletter will continue to be updated by email.
I have explained several times in different articles why I keep in touch with you by email. Simply put, the email system seems to be the only contact method that can hardly exist without relying on a certain platform. As long as your email service provider has not stopped the service, you can receive information through any email client, and you don’t have to worry about clicking on the article like in WeChat to suddenly turn into 404.
And even if the email push service I use is shut down one day, I can take everyone’s email list and continue to transfer to other service providers to send you messages. For example, because the number of subscribers is about to exceed the free limit of 2,000 mailchimp, in order to facilitate everyone to receive emails, I migrated from foreign mailchimp to Zhubai operated by an independent domestic development team.
In the future, in addition to subscribing via email, you can also use WeChat to subscribe to push notifications and read on the subscription interface. (Of course, email subscription is still the best way, and you can freely access external links)
What the newsletter includes
Just like the original idea of this newsletter, I will still share with you what I think, learn and think. Each issue of this free member newsletter will consist of three parts:
- Industry and Profession : It is conservatively estimated that more than half of the friends who subscribe to this newsletter are biomedical-related students and practitioners in the biomedical industry. I will share with you the latest research progress and industry trends in the field I have collected, including scientific research involving the participation of big names and leading companies in the field, as well as the latest industry trends worthy of attention.
- Reading and Thinking : I am still the person who likes to read things and think about problems when I have nothing to do, so I will share with you the good books and articles I usually read at home and abroad, and I will also report to you recently I thought about something again.
- Recommendation and search : The reason why we are what we are today is largely influenced by the people and things we come into contact with every day, so I will also recommend to you friends who have inspired and helped me a lot, and who have changed my life. my tools and habits. In addition, when I face problems, I will also ask you for help, looking for people and things that can help me.
Judging from the length of the previous article and the reading situation, the content of each time will be maintained at about 1,000 words, and try not to exceed 2,000 words.
What is a Paid Membership Program
If you click on the subscription interface of this Newsletter now, you will see the following interface.
In addition to the free subscription option, you can also see three paid subscription plans of different lengths.
In the paid content, I will focus on the review of research hotspots in the field of biomedicine and the interpretation of industry trends .
Currently tentative modules include: theme-based literature interpretation, industry-leading product exploration, introduction of domestic and foreign institutions, etc. The “industry” here mainly refers to the field of precision tumor treatment, related foreign and domestic biomedical companies, NGS testing companies, etc.
Different from the “Industry and Professional” section that focuses on the latest content in the free member newsletter, paid member content will not simply track hot spots and news .
- On the one hand, I hope that through my own screening and sorting out, I can try my best to ensure that the content is still valuable after a year of review;
- On the other hand, I hope to keep myself in a state of learning through relatively long writing and thinking, and show you the process.
It should be noted that I cannot present you very detailed (such as reproducing article charts or solving software runtime package errors) and very macro content (such as industry development trends in the next 5 years). The former stage has passed, and the latter stage must be beyond my current ability, and more professional teams are already providing these contents.
What I can present is a person who is in the industry and still has great curiosity about this field, what he is understanding and learning, and how he understands and learns.
I hope that after reading these contents, you can feel a little bit of my thinking, and I hope it can trigger your little thinking. Maybe my perspective is also subjective, but at least it can bring you some different perspectives.
Similar content, I have updated some recently, if you want to understand the writing style and content, you may wish to read it.
- FDA Issues Guidance on ctDNA Applied to Early-stage Solid Tumor Drug Development
- One of the ctDNA series: biological characteristics of ctDNA, detection technical issues and clinical application direction
- Also doing tumor NGS testing, how are the 9 companies listed on the US stock market doing?
- Chromosomal instability, why can 2022 use TCGA data to publish Nature
- Milestones in Targeted Cancer Therapy Spanning 60 Years
- Learn more about liquid biopsy with one conference agenda
- [Nature Reviews Cancer: 6 unsolved mysteries of precise tumor treatment in the next 10 years] ( Nature Cancer: Highly aneuploid non-small cell lung cancer is more sensitive to radiotherapy and concurrent immunotherapy
- Nature Genetics: Tumor aneuploidy in patients with low TMB can predict the efficacy of pan-cancer immunotherapy
- Nature Cancer: Highly aneuploid non-small cell lung cancer is more sensitive to radiotherapy and concurrent immunotherapy
The reason why I chose to present this part of the content as paid content is mainly due to three considerations:
- These contents are too professional and have very few audiences, considering that the reading experience is not suitable for presenting in an email with the previous contents;
- The creation of these contents takes a lot of energy, and paid subscription, which is essentially a contractual behavior, allows me to restrain myself to deliver better;
- As a person who has been carrying a huge loan in Shanghai for 30 years, if you can subsidize your daily meal tickets through writing and sharing, not only is it not shameful, but it is a happy thing.
Therefore, if you are a person like me who is in a related industry and is still curious about this field, these contents may be suitable for you; if you subscribe out of my personal support and love, I would like to sincerely grateful.
At present, this email newsletter has more than 1600 readers subscribed. You are welcome to join, receive free email newsletter every week or participate in the membership plan. Directly scan the QR code below or jump to the email newsletter subscription page to subscribe.
one more thing
If you have supported the Xiong Yan Xiong Yu podcast through the platform of “Love Power Generation”. If you need it, you can contact me (WeChat kaopu_bear), and I will be happy to send you the content of the paid membership plan for the next six months.
Thank you for your companionship and support, only this is the most precious. The future is long and the future can be expected.
The author of this article : bear who thinks about problems
Copyright statement : Unless otherwise stated, all articles on this blog are licensed under the Creative Commons Attribution-Non-Commercial Use-No Derivatives 4.0 International License Agreement (CC BY-NC-ND 4.0) .
If you are interested in this article, please subscribe to my “Xiong Yan Xiong Yu” member newsletter via email or WeChat. I will share with you the latest research progress in the field of biomedicine and what I think and learn. , click this link to subscribe for free.
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