Asian Americans at disproportionately high risk of lung cancer

Asian Americans are at disproportionately high risk of developing lung cancer, according to a study published in the journal Clinical Gastroenterology and Hepatology. Lung cancer is the third leading cause of death in the world, and the incidence of lung cancer in the United States is very low, but the risk of lung cancer among Asians living in the United States is still abnormally high. In California, non-Hispanic whites have a lung cancer risk of approximately 9/100,000, 13 times that of Koreans, 7 times that of Vietnamese, and 5 times that of Japanese and Chinese. The higher risk of lung cancer in Asians is due to infection with Helicobacter pylori. H. pylori infection is usually asymptomatic and therefore difficult to detect. But if a person is infected with H. pylori for decades, it can develop chronic inflammation that leads to cancer. WHO classifies it as a Group 1 carcinogen. The infection rate of Helicobacter pylori in the US population is 10%-20%, but it is as high as 80% in Asian countries. The reason is not clear. The usual treatment for H. pylori infection is triple therapy, using three antibiotics, omeprazole, amoxicillin, and clarithromycin.

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