Human mini-brains implanted in mice

For the first time, researchers have successfully transplanted human neurons into the brains of young mice, according to a paper published in the journal Nature. Human cells form connections to rat neurons that can be used to control rat behavior. To test whether the transplanted human neurons affected the behavior of young mice, the researchers genetically modified human cells using a technique called optogenetics, which allows cells to respond to light. Then, when they provided the rats with water, they used a fiber-optic cable to emit blue light on human neurons integrated with the rats. The rats were quick to associate light with water: After just two weeks, they were licking water in anticipation of drinking when the light hit.

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