Original link: https://hijiangtao.github.io/2022/12/14/My-COVID-19-Infection-Diary-and-QA/
infection record
Because I saw that the swimming pool was open for business, but a 48-hour nucleic acid certificate was required, so I went out to do a nucleic acid test last Thursday, which was the only time I went out for less than 10 minutes. 
up. Because I wanted to swim, I took a nucleic acid test, and then I became a nucleic acid positive, and I couldn’t swim.
During the seven days, the body temperature was monitored as follows. It took more than 3 days from the beginning of fever to the final stable reduction of fever. Among them, it was still observed that the last day of fever had repeated fever reduction and re-fever. In addition, until today, there will still be Occasionally, the body temperature reaches above 37 degrees, which may be related to going to work with illness and not getting enough rest. You can refer to:
In seven days, there are three symptoms, fever (fever), cold (runny nose, stuffy nose), cough (upper respiratory discomfort), plus my own guessed overall discomfort, the symptoms of these seven days can be roughly quantified as follows, you can see From the fourth day to the fifth day, the pain was really worse, but I still have a cough today, which shows that the disease has not completely disappeared. Since I only took antipyretic drugs, other symptoms have to be borne by the immune system until rehabilitation:
Medication, diet and rest and advice
- Although you can’t rest quietly when you have a high fever and cough, you still have to seize the opportunity to sleep and rest as much as possible to restore your physical strength and continue to fight the virus.
- Drink plenty of water to help metabolism. Warm water is recommended, avoid boiling water. If you ask why you avoid boiling water, two words – burn your mouth.
- Drink more milk and eat eggs to supplement protein. Protein is converted into amino acids in the body, which can be converted into antibodies and energy for the body to continue working.
- Ibuprofen or Tylenol can be considered as antipyretic drugs. Do not mix single drugs, and take them strictly according to the dosage and method after checking the drug instructions; on the basis of taking antipyretic drugs, if you have a persistent high fever for 3 days or more, do not delay , See a doctor in time.
- Eat more fruits and vegetables, you can consider honey water or electrolyte water, in addition to replenishing body energy, it may be helpful to relieve cough and restore physical strength.
- Stay away from pornography while sick, as some exercises are known to lower the body’s resistance.
- Don’t believe that early is good, and the virus strains have various mutations. There is no such thing as “at least half a year at a time”. In this long battle, try to protect yourself as much as possible to avoid infection.
- At present, the material reserve plan is still valid. I briefly mentioned the reserve list of medical care and medicine in the food reserve plan. For details, see the “Food Reserve List” ; Reserves are also necessary.
- At present, when you are in good health and have no symptoms, you can mix some medicines in proportion according to the number of people in your family, so as to prevent the continuous peak of the disease from impacting on the supply of medicines, resulting in the situation that the medicines needed by the family cannot be met in time; we know that , Supply and demand will eventually be balanced, but the smooth passing of the peak period also depends on some preparedness plans.
- Don’t think about watching dramas or reading books when you are resting. My experience tells me that even though I couldn’t sleep well at that time, I was really tired even opening my eyes; I pray that my immune system will fight hard.
Q&A
After readers and friends in the early days wrote to express some doubts about the virus in their hearts (in fact, no one wrote, they were all fabricated by myself), I hereby selected some representative questions and answered them here, hoping to help to everyone.
Q: I have already taken ibuprofen/Tylenol, can I take Ganmaoling and other granules to assist in the treatment?
Answer: I don’t know if it can cure the new crown, but if you eat it wrong, you can send it away directly. Take single-ingredient antipyretics honestly, don’t believe in any antipyretic/cure methods, believe in pathology, and believe in science.
Q: What should I do if I can’t exercise during the home treatment and my body’s resistance becomes weak?
Answer: No, you will start coughing around the 4th day, which will help you cough up your abdominal muscles.
Question: Brothers and sisters, has anyone had a fever of 38 degrees on the first day and took ibuprofen and the fever subsided to 35.5 degrees the next day?
Answer: Your immune system hasn’t fought for a long time, so let’s do it this time.
ask: Are there any taboos after eating?
Answer: can not eat Meat.
Question: I have stockpiled the antigens, bought the medicine, and cleaned up the house. I am waiting for the virus to visit, but what should I do if I am not yet positive?
Answer: Don’t be afraid, although you are not positive, you can look at your stock account, it may have been negative long ago.
ask: Do you have a bitter feeling in your mouth after taking it?
Answer: Generally speaking, bitterness in the mouth is a normal symptom of illness, but it is not ruled out that some people’s mouths will become sweet, and drinking water will feel sweet; if not only bitterness in the mouth, but also bitterness in everything, it may not be caused by illness Come, but brought by life, fall!
An overview of the body temperature regulation mechanism and the principle of fever reduction
body temperature regulation mechanism
The human temperature regulation center is located in the hypothalamus. Its special nerve tissue can detect the temperature of the human body at all times, and has a set “temperature regulation point”. To put it simply, when the body temperature is higher than the body temperature setting point, the body promotes heat dissipation; on the contrary, when the body temperature is low, the body promotes heat production and reduces heat dissipation.
When the surrounding temperature is too high, thermoreceptors are activated, which in turn transmit information to the brain. When the temperature of the thermoregulatory center is higher than the thermoregulation point, the first half of it will be excited, triggering the body’s blood vessel expansion and sweating function through the nervous system, so as to achieve the purpose of heat dissipation and lowering body temperature. These functions primarily include increased blood flow and increased perspiration. Increased blood flow can make the heat of the blood more exchanged with the external environment through the skin, thereby expelling the heat from the body. If this is not enough to lower the temperature, the hypothalamus regulates through various mechanisms, causing the skin to sweat, and the heat is forcibly removed through the evaporation of sweat.
When the ambient temperature is too low, the second half of the hypothalamus will also receive signals from cold receptors, and then become excited, and also cause various functions of the human body to operate through the nervous system, increase heat production, reduce heat loss, and increase body temperature . The human body mainly reduces heat loss by shrinking capillaries and reducing heat exchange between blood and the outside world. When this method is not enough to raise the body temperature, the human body will increase the metabolic rate of cells through methods such as chills, thereby increasing heat production.
The body temperature of the human body can be maintained at a stable level for a long time only through the cooperation and interaction of the above two methods.
Principles of inflammation and fever
Inflammatory response, cell membrane phospholipids release arachidonic acid (AA) under the action of phospholipase PLA2, arachidonic acid generates prostaglandin (PG) and thromboxane (TXA2) through the action of COX, and then a series of enzymes act to generate white three Inflammatory factors such as alkene (LG), lipoxin, and hydroxyepoxin. Prostaglandins (PG) are highly active in inflammatory reactions, and together with leukotrienes, induce inflammatory cells, chemoattract inflammatory mediators, and induce the immune system to produce a cascade chain reaction.
Among them, prostaglandin E2 can increase body temperature, and prostaglandin E2 can also cause muscle, bone, and joint pain, which is why body pain often occurs when the body is hot.
Antipyretics and their principles
Antipyretics are medicines that lower body temperature and relieve fever symptoms. Most antipyretics have other uses. For example, the most common antipyretics in the United States are usually ibuprofen and aspirin, which are mainly NSAIDs used as pain relievers, but also have antipyretic effects.
Since fever is part of the body’s immune response, there is some debate about the use of these drugs.
Among them, taking ibuprofen as an example, its drug withdrawal principle is related to its drug reaction. Human body temperature regulation is controlled by the hypothalamus. When the drug reaction of ibuprofen acts on the hypothalamus, the hypothalamus will react to lower the body temperature. .
Ibuprofen is a non-steroidal anti-inflammatory analgesic, and it is an inhibitor of cyclooxygenase. After taking it, it can inhibit the production of prostaglandin E2 from the metabolism of arachidonic acid in the hypothalamus of the brain through drug reactions. Some inhibit the production and release of some cytokines, which are one of the body’s pyrogens, such as tumor necrosis factor, thereby causing an antipyretic effect.
In short, ibuprofen inhibits the synthesis of prostaglandins and has analgesic, antipyretic and anti-inflammatory effects.
other references
- food storage list
- Epidemic Prevention Diary
- The Comprehensive Group of the Joint Prevention and Control Mechanism of the State Council’s Response to the Novel Coronavirus Pneumonia Epidemic “Novel Coronavirus Pneumonia Prevention and Control Plan (Ninth Edition)”
- World Health Organization’s Rehabilitation Guidebook: Self-management of COVID-19-Related Illness (Second Edition)
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