According to a study published in the journal Cell, researchers at the Weizmann Institute of Science in Israel used mouse stem cells to create a mouse embryo model with an early-stage brain and beating heart, a process that does not require sperm-egg union. The embryonic model survived for 8.5 days, nearly halfway through the mouse’s 20-day gestation period, by which time many organs had developed their early appearances, including a beating heart, well-folded brain, neural tube and gut. Compared with natural mouse embryos, the bred embryo model has 95% similarity in internal structure shape and cellular gene expression pattern, and various organs in the embryo model have relevant markers, indicating that they are functional. The researchers said that in the future, it is expected to further cultivate artificial human embryo-like structures on the basis of this research, so as to provide tissues, organs, etc. that can be used for transplantation.
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